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Neuro-MoD: Neuroplasticity With Motor Development
Sponsor: University of Wisconsin, Madison
Summary
This study is for infants and toddlers between 8 and 24 months old who use one arm and/or hand differently following a perinatal brain injury. This is a time when investigators think they can best help improve how the brain controls movement. Investigators are testing whether the combination of transcutaneous auricular vagus nerve stimulation (taVNS) with 40 hours of constraint-induced movement therapy (CIMT) can help infants move their weaker arm and hand better and make the brain pathways for movement stronger.
Official title: Harnessing Early Neuroplasticity in Infants With Perinatal Brain Injury: A Study of Combined Transcutaneous Auricular Vagal Nerve Stimulation (taVNS) Paired With Constraint Induced Movement Therapy (CIMT) and Transcranial Magnetic Stimulation (TMS)
Key Details
Gender
All
Age Range
8 Months - 24 Months
Study Type
INTERVENTIONAL
Enrollment
8
Start Date
2026-10
Completion Date
2027-06
Last Updated
2026-10-19
Healthy Volunteers
No
Conditions
Interventions
Constraint-Induced Movement Therapy (CIMT)
CIMT involves placing a mitt constraint on the stronger arm and hand while encouraging your child to use the weaker arm and hand during intensive therapy sessions.
Transcutaneous auricular vagus nerve stimulation (taVNS)
Stimulates a nerve by the ear, called the vagus nerve, that may enhance learning motor skills.
Locations (1)
University of Wisconsin - Madison
Madison, Wisconsin, United States