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Analyzing Retinal Microanatomy in Retinopathy of Prematurity to Improve Care
Sponsor: Duke University
Summary
Retinopathy of prematurity (ROP) is a disorder of development of the retina and its vasculature that can impact vision in vulnerable preterm neonates for a lifetime. A major barrier to improving ROP outcomes is the lack of easy access and low stress means to obtain objective measures of ROP disease severity across the retina in these infants. The long-term goal of this program is to provide information which will improve preterm infant health and vision via objective bedside imaging and analysis that characterizes retina-wide ROP level of disease, its response to treatment and development, and to rapidly translate this for better early intervention and improved future vision care.
Official title: Analyzing Retinal Microanatomy in Retinopathy of Prematurity to Improve Care 3 (BabySTEPS3)
Key Details
Gender
All
Age Range
0 Days - 9 Months
Study Type
INTERVENTIONAL
Enrollment
175
Start Date
2026-10-01
Completion Date
2031-12-31
Last Updated
2026-09-08
Healthy Volunteers
No
Conditions
Interventions
Ultra-widefield Optical Coherence Tomography (UWF-OCT)
Handheld retinal OCT imaging at the bedside or in clinic with an ultra-widefield handheld optical coherence tomography
Wide-field ophthalmic imaging system
Handheld wide-field ophthalmic fundus imaging at the bedside or in clinic
Locations (2)
Duke University Eye Center
Durham, North Carolina, United States
University of Pennsylvania, Center for Preventive Ophthalmology and Biostatistics
Philadelphia, Pennsylvania, United States