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SAFE (Self-Administration of Flumist to ImprovE Uptake: A Household-Based Cluster Randomized Trial)
Sponsor: McMaster University
Summary
The flu is a health risk for Canadians. It causes up to 15,000 hospitalizations every year and is one of the top 10 causes of death. Getting a flu vaccine is the best way to prevent the flu and any severe complications. Unfortunately, many Canadians do not get the flu vaccine. A recent survey found that less than a quarter of healthy adults got the flu vaccine. In Canada, current standard access to influenza vaccination is at physician offices, public health clinics, or pharmacy. Therefore, this study is testing a novel access route to influenza vaccine. This study will answer the question: "Will self-administration at home of FLUMIST through a pharmacy pick up model increase uptake of influenza vaccination compared to usual care?" FLUMIST is a needle-free vaccine given as a nasal spray. Households will be randomly chosen to either be offered the FLUMIST vaccine that can be given at home or to make their own choice for the flu season, which may or may not include vaccination.
Key Details
Gender
All
Age Range
2 Years - 59 Years
Study Type
INTERVENTIONAL
Enrollment
966
Start Date
2026-10-15
Completion Date
2027-02-15
Last Updated
2026-07-31
Healthy Volunteers
Yes
Conditions
Interventions
LAIV FLUMIST
Children, adolescents, adults 9 to 59 years - 1 dose (0.2 ml).
Locations (1)
McMaster University
Hamilton, Ontario, Canada