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Niaoduqing Granules in Older Adults With Impaired Kidney Function
Sponsor: Huashan Hospital
Summary
This prospective real-world study will evaluate the clinical benefits of Niaoduqing Granules in older adults with impaired kidney function. Approximately 300 participants aged over 60 years with stage 3 to 5 chronic kidney disease who are not receiving dialysis will be enrolled at Huashan Hospital, Fudan University. The study will examine whether treatment with Niaoduqing Granules is associated with slower kidney function decline and improvements in nutrition, frailty, and other health outcomes. Participants will receive 5 g of Niaoduqing Granules three times daily after meals for 12 months, while continuing their usual treatment for chronic diseases as directed by their physicians. Kidney function, laboratory results, nutritional status, frailty, cardiovascular and cerebrovascular events, and survival will be assessed during follow-up. Blood, urine, and stool samples will also be collected to study changes in gut microorganisms and blood metabolites that may help explain how Niaoduqing Granules affect health. Participants will be followed for up to 60 months.
Official title: A Study of the Clinical Benefits of Niaoduqing Granules in Older Adults With Impaired Renal Function
Key Details
Gender
All
Age Range
61 Years - Any
Study Type
INTERVENTIONAL
Enrollment
300
Start Date
2025-12-01
Completion Date
2030-11-30
Last Updated
2026-08-03
Healthy Volunteers
No
Conditions
Interventions
Intervention Name
Niaoduqing Granules will be administered orally at a dose of 5 g three times daily at 6:00, 12:00, and 18:00 after meals with warm water for 12 months. Usual treatments for chronic kidney disease, age-related comorbidities, and other chronic conditions may be continued or adjusted according to specialist recommendations.
Locations (1)
Huashan Hospital, Fudan University
Shanghai, Shanghai Municipality, China