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Povidone Iodine for Caries Prevention
Sponsor: Jeffrey A. Banas
Summary
The goal of this clinical trial is to learn if Povidone Iodine works to prevent tooth decay and suppress the mouth germs responsible for tooth decay. The main questions it aims to answer are: 1. How will home use of Povidone Iodine, as an adjunct treatment to standard dental care, reduce the incidence of tooth decay? 2. How will home use of Povidone Iodine reduce the mouth germs responsible for tooth decay? 3. If Povidone Iodine use is accompanied by probiotic use, will its effectiveness be even better than Povidone Iodine alone? Participants will: 1. Provide a plaque sample at the beginning of the study. 2. Swab their children's teeth once a week for one month and then monthly thereafter. Some participants may be asked to use probiotic drops nightly after brushing their teeth. 3. Keep a record of compliance. 4. Return every 6 months for a dental exam and to provide a plaque sample. Keep a diary of their symptoms and the number of times they use a rescue inhaler
Official title: Povidone Iodine to Prevent Early Childhood Caries
Key Details
Gender
All
Age Range
1 Year - 3 Years
Study Type
INTERVENTIONAL
Enrollment
174
Start Date
2026-08-03
Completion Date
2028-06-30
Last Updated
2026-08-03
Healthy Volunteers
Yes
Conditions
Interventions
Povidone Iodine 5% Soln,Top,Kit
Home use of Povidone Iodine administered by swabbing teeth; weekly for the 1st month, monthly thereafter.
Probiotics
Home use of Povidone Iodine coupled with daily use of a probiotic.
Placebo
Placebo for the Povidone Iodine
Locations (1)
University of Iowa College of Dentistry
Iowa City, Iowa, United States