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Assessing Treatment With High-phenolic EVOO Supplements for Neurovascular Activity
Sponsor: Augusta University
Summary
The goal of this clinical trial is to determine whether the extra-virgin olive oil (EVOO) phenolic dietary supplement can improve memory function and modulate biomarkers among individuals with mild cognitive impairment (MCI). The main questions it aims to answer are: * Does dietary supplementation with EVOO phenolics improve cognitive function? * What would be the effect of the EVOO dietary supplement on other MCI-related biomarkers, including vascular function and biological pathways? Researchers will compare the EVOO dietary supplements with a placebo (a look-alike substance that contains no EVOO phenolics) Participants will: * Take EVOO dietary supplements or a placebo daily for 6 months * Visit the study site during the 6-month study for screening and testing.
Official title: Dietary Supplementation With EVOO Phenolics Prevents MCI Progression to Alzheimer's Disease
Key Details
Gender
All
Age Range
50 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2026-09-01
Completion Date
2028-08-31
Last Updated
2026-08-03
Healthy Volunteers
No
Conditions
Interventions
EVOO-phenolics dietary supplement
EVOO phenolic dietary supplement which is standardized to contain10 mg of EVOO total phenolics
Placebo
Placebo
Locations (1)
Georgia prevention institute
Augusta, Georgia, United States