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NOT YET RECRUITING
NCT07741773
NA

Assessing Treatment With High-phenolic EVOO Supplements for Neurovascular Activity

Sponsor: Augusta University

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to determine whether the extra-virgin olive oil (EVOO) phenolic dietary supplement can improve memory function and modulate biomarkers among individuals with mild cognitive impairment (MCI). The main questions it aims to answer are: * Does dietary supplementation with EVOO phenolics improve cognitive function? * What would be the effect of the EVOO dietary supplement on other MCI-related biomarkers, including vascular function and biological pathways? Researchers will compare the EVOO dietary supplements with a placebo (a look-alike substance that contains no EVOO phenolics) Participants will: * Take EVOO dietary supplements or a placebo daily for 6 months * Visit the study site during the 6-month study for screening and testing.

Official title: Dietary Supplementation With EVOO Phenolics Prevents MCI Progression to Alzheimer's Disease

Key Details

Gender

All

Age Range

50 Years - 70 Years

Study Type

INTERVENTIONAL

Enrollment

20

Start Date

2026-09-01

Completion Date

2028-08-31

Last Updated

2026-08-03

Healthy Volunteers

No

Interventions

DIETARY_SUPPLEMENT

EVOO-phenolics dietary supplement

EVOO phenolic dietary supplement which is standardized to contain10 mg of EVOO total phenolics

DIETARY_SUPPLEMENT

Placebo

Placebo

Locations (1)

Georgia prevention institute

Augusta, Georgia, United States