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NOT YET RECRUITING
NCT07741890
PHASE2

aDAPt-ANOCA: Dapagliflozin for the Treatment of Angina With Non-Obstructive Coronary Artery Disease (ANOCA)

Sponsor: The Christ Hospital

View on ClinicalTrials.gov

Summary

The primary purpose of this study is to evaluate the efficacy of DAPA for the treatment of coronary microvascular dysfunction (CMD) among patients with angina and no obstructive coronary artery disease (ANOCA) and established CMD as compared to placebo.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

120

Start Date

2026-09-01

Completion Date

2029-03-01

Last Updated

2026-08-03

Healthy Volunteers

No

Interventions

DRUG

Dapagliflozin (10mg Tab)

The study will be double blinded by over encapsulation of Dapagliflozin with a matching lactose powder capsule used for the placebo group. All enrolled participants who meet inclusion / exclusion will receive either 10 mg Dapagliflozin (10mg) for 180 days, or placebo, randomized 1:1.

DRUG

Placebo ( FE)

Over encapsulated placebo to match active drug.