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NOT YET RECRUITING
NCT07742319
NA

How Differences in the Composition of Microorganisms in the Soil Affect the Microorganisms in the Human Gut, Through the Vegetables That Grow in it: a Process Pilot Study With Healthy Participants

Sponsor: Leiden University Medical Center

View on ClinicalTrials.gov

Summary

There are two objectives for this clinical trial. The first is to test whether, with the current logistics and study setup it is possible to perform the study well and see where there might be bottlenecks we couldn't predict. The second objective is to investigate the relation between the composition of the microorganisms in the soil, the crops that grow in that soil, and the human gut. During the study participants will drink three vegetable smoothies a day, for two periods of one week. The only difference between the two periods is whether the vegetables come from a farm with a low diversity of microorganisms in the soil or a high diversity. Participants will be asked to give blood samples and turn in fecal samples before and after each period.

Official title: The Effect of Soil Biodiversity on Human Gut Microbiome: a Process Pilot Study (The HUMANITAS Study)

Key Details

Gender

All

Age Range

18 Years - 70 Years

Study Type

INTERVENTIONAL

Enrollment

10

Start Date

2026-08

Completion Date

2026-09

Last Updated

2026-08-03

Healthy Volunteers

Yes

Conditions

Interventions

OTHER

Low diversity vegetable smoothie

Vegetable smoothie prepared with crops grown in low-microbial diversity soil

OTHER

High diversity vegetable smoothie

Vegetable smoothie prepared with crops grown in high-microbial diversity soil

Locations (1)

Leids Universitair Medisch Centrum

Leiden, South Holland, Netherlands