Clinical Research Directory

Inclusion Criteria: 1. Aged 7-17 years at enrollment. 2. Meeting at least one of the following conditions: Having at least one first-degree relative with a depressive disorder, anxiety disorder, or obsessive-compulsive disorder; or exhibiting clinically relevant but subthreshold depressive, anxiety, obsessive-compulsive, or repetitive behavioral symptoms. 3. Not meeting the full diagnostic criteria for a depressive disorder, anxiety disorder, or obsessive-compulsive disorder at baseline, as assessed using the K-SADS-PL. 4. Willing and able to participate in the scheduled assessments and follow-up visits. 5. Written informed consent provided by a parent or legal guardian and assent provided by the participant Exclusion Criteria: 1. A current or previous diagnosis of a depressive disorder, anxiety disorder, or obsessive-compulsive disorder. 2. A severe psychiatric condition requiring immediate clinical intervention, including acute suicide risk, a psychotic disorder, or a bipolar disorder. 3. A major neurological disorder, severe head injury, or serious or unstable medical condition that may interfere with study participation. 4. Intellectual or cognitive impairment that prevents the participant from understanding or completing the study assessments. 5. Inability or unwillingness of the participant or legal guardian to comply with the study procedures.