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RECRUITING
NCT07745426
PHASE2

Clinical Study Comparing Diosmin vs Rebamipide as Adjuvant Therapies vs Conventional Therapy in Patients With Rheumatoid Arthritis

Sponsor: Tanta University

View on ClinicalTrials.gov

Summary

This study will be a randomized controlled parallel study that will be conducted on 66 patients with active rheumatoid arthritis who will be diagnosed with RA according to American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR, 2010). The patients will be recruited from Outpatient Clinic of Rheumatology, Physical Medicine, Rheumatology and Rehabilitation Department, Tanta University Hospital, Tanta, Egypt. The study duration will be 3 months. The patients will be randomized into three groups: \- Group 1 (control group): will include 22 patients who will receive the conventional therapy for RA for 3 months. \- Group 2 (diosmin group): will include 22 patients who will receive the conventional therapy for RA plus 1000 mg diosmin once daily for 3 months. \- Group 3 (rebamipide group): will include 22 patients who will receive the conventional therapy for RA plus 100 mg rebamipide three times daily for 3 months.

Key Details

Gender

All

Age Range

18 Years - 70 Years

Study Type

INTERVENTIONAL

Enrollment

66

Start Date

2026-08-01

Completion Date

2027-08-01

Last Updated

2026-08-04

Healthy Volunteers

No

Interventions

DRUG

Diosmin

1000 mg diosmin once daily for 3 months

DRUG

Rebamipide 100mg

100 mg rebamipide three times daily for 3 months

DRUG

Convential medical treatment

conventional medical treatment for RA

Locations (1)

Faculty of Pharmacy Tanta University

Tanta, Egypt