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A Research Study to Compare Two Different Versions of Injectable Cagrilintide and Placebo in People With Excess Body Weight
Sponsor: Novo Nordisk A/S
Summary
The purpose of this clinical study is to look at how well a study medicine called cagrilintide helps people living with excess body weight to lose weight. Participants will either get cagrilintide, the active study medicine being tested or placebo, a medicine that has no active medicine in it. Which treatment participants get is decided by chance. Cagrilintide is a new medicine under development that doctors cannot prescribe yet, but it has been tested in humans before. Participants will be in this clinical study for about 9 months.
Official title: A Placebo-controlled Comparability Study to Compare Two Presentations of Cagrilintide for Weight Management in Participants With Overweight or Obesity
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
285
Start Date
2026-08-04
Completion Date
2027-07-06
Last Updated
2026-08-04
Healthy Volunteers
No
Conditions
Interventions
Cagrilintide
Cagrilintide will be administered subcutaneously.
Placebo cagrilintide
Placebo matched to cagrilintide will be administered subcutaneously.
Placebo semaglutide
Placebo matched to semaglutide will be administered subcutaneously.
Locations (36)
Hope Clin Res & Wellness
Conyers, Georgia, United States
East West Med Res Inst
Honolulu, Hawaii, United States
Walgreens - Store 11760
Oak Park, Illinois, United States
Midwest Inst For Clin Res
Indianapolis, Indiana, United States
The Alliance for Multispecialty Research LLC AMR
Lexington, Kentucky, United States
PharmQuest
Greensboro, North Carolina, United States
KDCILM, LLC & Accellacare US, Inc.
Wilmington, North Carolina, United States
Coastal Carolina Res Ctr
North Charleston, South Carolina, United States
Health Res of Hampton Roads
Newport News, Virginia, United States
National Clin Res Inc.
Richmond, Virginia, United States
Selma Medical Associates
Winchester, Virginia, United States
General Hospital Of Athens Alexandra - Department of Endocrinology, Diabetes Center
Athens, Greece
General Hospital Of Athens G Gennimatas - Department of Endocrinology
Athens, Greece
General Hospital Venizeleio-Pananeio - Diabetic Clinic
Irakleio, Greece
Athens Medical Center S.A. (Iatriko Peristeriou) - Diabetes, obesity and cardiometabolic diseases department
Peristeri, Greece
Ippokratio General Hospital Of Thessaloniki - B' Internal Medicine clinic
Thessaloniki, Greece
St. Luke's Hospital S.A. - Endocrinology Department and Obesity Clinic
Thessaloniki, Greece
Stúdium Egészségház Kft.
Kalocsa, Bács-Kiskun county, Hungary
Borbánya Praxis E.Ü. Kft.
Nyíregyháza, Szabolcs-Szatmar Varmegye, Hungary
Trial Pharma Kft.
Kecskemét, Hungary
KomplexLabor Diagnosztika Kft.
Szeged, Hungary
ULS Do Oeste E.P.E. - Unidade Caldas da Rainha_CAMI - Unidade de Diabetes
Caldas da Rainha, Portugal
ULS Do Baixo Mondego, E.P.E. - HDFF_Serviço Cirurgia (Esp. Endocrinologia)
Figueira da Foz Municipality, Portugal
Hospital São Francisco, S.A_EECC
Leiria, Portugal
APDP - Associação Protectora dos Diabéticos de Portugal
Lisbon, Portugal
CVP Hospital Cruz Vermelha_Cardiologia
Lisbon, Portugal
ULS De Gaia/Espinho_H.Santos Silva_Endocrinologia
Vila Nova de Gaia, Portugal
Endocrinology, Diabetes and Metabolism Diseases Clinic
Belgrade, Serbia
Institute for Cardiovascular Diseases of Vojvodina - Sremska Kamenica
Kamenitz, Serbia
Clinical Centre Nis, Endocrinology, Diabetes and Metabolism
Niš, Serbia
University Clinical Centre Nis, Clinic for Cardiology
Niš, Serbia
Clin. Centre Vojvodina, Clin. endocr., diab. and met. dis.
Novi Sad, Serbia
Skånes Universitets Sjukhus
Lund, Sweden
Forsåker vårdcentral
Mölndal, Sweden
Örebro US - Överviktsenheten
Örebro, Sweden
Dalecarlia Clinical Research AB
Rättvik, Sweden