Clinical Research Directory
Browse clinical research sites, groups, and studies.
OCCUPATİONAL THERAPY APPROACH İN ARX-RELATED EPİLEPSY
Sponsor: Uskudar University
Summary
This study evaluated the effects of medical ketogenic diet therapy combined with occupational therapy in children with ARX-related epilepsy. Twenty children were included. Ten children receiving a ketogenic diet formed the experimental group, and ten children not receiving a ketogenic diet formed the control group. Both groups received occupational therapy for 16 weeks. Assessments were performed at baseline, week 8, and week 16. Seizure frequency, motor performance, balance, sensory processing, chewing performance, eating behaviors, and health-related quality of life were evaluated.
Official title: EVIDENCE-BASED KETOGENIC DIET PRACTICES IN INDIVIDUALS WITH ARX GENE MUTATION AND EPILEPSY: AN OCCUPATIONAL THERAPY PERSPECTIVE
Key Details
Gender
All
Age Range
4 Years - 7 Years
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2026-02-02
Completion Date
2026-05-25
Last Updated
2026-08-04
Healthy Volunteers
No
Conditions
Interventions
Occupational Therapy
Participants received individualized occupational therapy sessions twice weekly for 16 weeks. The intervention was planned according to each child's clinical and functional needs and addressed motor performance, balance, sensory processing, feeding-related skills, chewing performance, and participation in daily activities.
Medikal Ketogenic Diet Therapy
Participants in the experimental arm continued medical ketogenic diet therapy prescribed and monitored by their clinical neurology and nutrition teams. The ketogenic diet was not initiated or assigned by the occupational therapy researcher.
Locations (1)
Ilk Evre Special Education and Rehabilitation Center
Istanbul, Istanbul, Turkey (Türkiye)