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Swap Anesthetic Versus Continuous Desflurane in Adults Undergoing Bariatric Surgery
Sponsor: Clínica Dávila
Summary
This randomized, parallel-group, non-inferiority clinical trial aims to evaluate whether an anesthetic swap strategy consisting of sevoflurane followed by desflurane 30 minutes before the end of surgery is non-inferior to continuous desflurane anesthesia with respect to extubation time in adults undergoing elective laparoscopic bariatric surgery. Secondary outcomes include time to achieve a Patient State Index (PSi) greater than 80, time to achieve an Aldrete score of at least 8, incidence of postoperative nausea and vomiting, post-anesthesia care unit length of stay, and desflurane-related costs.
Official title: Desflurane Versus Sevoflurane-Desflurane Swap in Adults Undergoing Bariatric Surgery: A Randomized Non-Inferiority Trial on Extubation Time
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
82
Start Date
2026-08-03
Completion Date
2027-04
Last Updated
2026-08-05
Healthy Volunteers
No
Conditions
Interventions
Desflurane
Desflurane administered as the inhalational anesthetic throughout the surgical procedure.
Sevoflurane-Desflurane
Sevoflurane administered during the initial phase of surgery followed by desflurane beginning 30 minutes before surgical closure.
Locations (1)
Clínica Dávila
Santiago, Santiago Metropolitan, Chile