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NOT YET RECRUITING
NCT07748351
PHASE1

A Clinical Trial of Multiple Formulations of MK-4082 in Healthy Overweight and Obese Participants (MK-4082-007)

Sponsor: Merck Sharp & Dohme LLC

View on ClinicalTrials.gov

Summary

Researchers are looking for new weight loss medicines for people with higher body weight. The study medicine, MK-4082, is different from similar weight loss medicines because people take it as a pill instead of an injection. Before giving a study medicine to people with a health condition, researchers first do studies to find a safe dose level (amount) and formulation (version) of the study medicine that can be used in future studies. The goals of this study are to learn about: The safety of different formulations of MK-4082 and if people tolerate them What happens to different formulations of MK-4082 in a person's body over time

Official title: A Study to Evaluate the Relative Bioavailability of Multiple Formulations of MK-4082 in Overweight/Obese Participants

Key Details

Gender

All

Age Range

18 Years - 60 Years

Study Type

INTERVENTIONAL

Enrollment

48

Start Date

2026-08-25

Completion Date

2026-12-15

Last Updated

2026-08-05

Healthy Volunteers

Yes

Conditions

Interventions

DRUG

MK-4082 Formulation 1 (F1)

Oral Tablet

DRUG

MK-4082 Formulation 2 (F2)

Oral Tablet

DRUG

MK-4082 Formulation 4 (F4)

Oral Tablet