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Photon-Counting CT for Detection of Small Gastrointestinal Lesions
Sponsor: The Second Affiliated Hospital of Chongqing Medical University
Summary
This comparative matched-cohort study aims to evaluate the diagnostic performance of contrast-enhanced photon-counting computed tomography (PCCT) for detecting small gastrointestinal lesions compared with energy-integrating detector dual-energy computed tomography (DECT). The study includes a prospectively enrolled PCCT cohort and a retrospectively identified DECT cohort. Endoscopy with histopathology serves as the reference standard. Primary evaluation focuses on lesion detection, with additional assessment of lesion characterization, image quality, quantitative imaging parameters, and interobserver agreement.
Official title: Photon-Counting CT for Detection of Small Gastrointestinal Lesions: Comparison With Energy-Integrating Detector Dual-Energy CT and Prospective Clinical Implementation
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
OBSERVATIONAL
Enrollment
1762
Start Date
2023-09-18
Completion Date
2026-05-21
Last Updated
2026-08-10
Healthy Volunteers
No
Conditions
Interventions
Contrast-Enhanced Photon-Counting Computed Tomography
Contrast-enhanced abdominal photon-counting computed tomography performed for the detection and characterization of small gastrointestinal lesions.
Contrast-Enhanced Energy-Integrating Detector Dual-Energy Computed Tomography
Contrast-enhanced abdominal energy-integrating detector dual-energy computed tomography performed for comparison of diagnostic performance in detecting and characterizing small gastrointestinal lesions.
Locations (1)
The Second Affiliated Hospital of Chongqing Medical University
Chongqing, Chongqing Municipality, China