Clinical Research Directory

Inclusion Criteria: * Age ≥18 years； * Confirmed lower extremity deep vein thrombosis (DVT) by imaging, meeting at least one of the following: (1) acute iliofemoral or femoropopliteal DVT; or (2) subacute iliofemoral DVT; * Investigator-assessed life expectancy ≥1 year; * Willing to participate in this study and provide written informed consent. Exclusion Criteria: * Infection at the puncture site or severe systemic infection; * Inability to establish vascular access or difficulty in advancing the guidewire through the lesion; * Hemodynamically unstable pulmonary embolism; * The target lesion thrombosis is recurrent after prior interventional therapy; * A venous stent has been implanted in the target lesion, or the presence of an inferior vena cava filter that interferes with device deployment; * Bilateral lower extremity deep vein thrombosis requiring thrombectomy in the same procedure; * Active bleeding within the past 30 days, including severe intracranial, gastrointestinal, or urinary tract bleeding; * History of hemorrhagic or ischemic stroke within the past 30 days; * Known severe coagulation disorder or bleeding tendency; * Severe hepatic or renal impairment; * Known allergy or significant hypersensitivity to iodine-based contrast media, thrombolytic agents, anticoagulants, or antiplatelet drugs; * Known conditions such as severe hyperthyroidism, multiple myeloma, or severe heart failure that preclude tolerance to percutaneous transluminal angioplasty; * Pregnant or lactating women, or women planning to become pregnant during the study period; * Currently participating in any other clinical trial of a drug or medical device; * Any other condition that, in the investigator's judgment, makes the subject ineligible for participation in this trial.