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Assessing the Role of Proton Pump Inhibitors in Reducing Aspiration Incidence in Pediatric Laryngomalacia Cases
Sponsor: Minia University
Summary
Laryngomalacia is the most common congenital laryngeal anomaly in children and is frequently associated with aspiration. This randomized controlled study aims to assess the role of proton pump inhibitor (PPI) therapy in reducing the incidence of aspiration in pediatric patients with laryngomalacia. Eligible participants will be randomly assigned to either a PPI treatment group or a control group. Clinical and swallowing assessments will be performed to compare aspiration incidence and swallowing outcomes between the two groups
Key Details
Gender
All
Age Range
6 Months - 5 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2026-04-28
Completion Date
2026-12-31
Last Updated
2026-08-06
Healthy Volunteers
No
Conditions
Interventions
PPI
Proton pump inhibitor therapy administered according to the study protocol
vitamin D
Vitamin D supplementation administered according to the study protocol.
feeding instruction
Standard feeding instructions provided to caregivers according to the study protocol.
Locations (1)
faculty of Medicine, Minia University
Minya, Minya Governorate, Egypt