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Intraoperative Laser Speckle Imaging Predicts Early Renal Function After Kidney Transplantation
Sponsor: The Second Affiliated Hospital of Chongqing Medical University
Summary
This observational study aims to explore the predictive value of intraoperative laser speckle contrast imaging for early postoperative renal function in kidney transplant recipients. The core research question is: What is the efficacy of intraoperative laser speckle contrast imaging in predicting early postoperative renal function among kidney transplant patients? This study will enroll kidney transplant patients who undergo intraoperative laser speckle contrast imaging and collect relevant evaluation data. Last updated on February 27, 2025
Official title: An Observational Study on the Predictive Value of Intraoperative Laser Speckle Contrast Imaging for Early Postoperative Renal Function in Kidney Transplant Recipients
Key Details
Gender
All
Age Range
Any - Any
Study Type
OBSERVATIONAL
Enrollment
80
Start Date
2024-08-01
Completion Date
2025-02-27
Last Updated
2026-08-07
Healthy Volunteers
No
Conditions
Interventions
laser speckle contrast imaging (LSCI)
Before abdominal closure, renal microcirculation was assessed using the RFLSI-ZW laser speckle contrast imaging (LSCI) system (RWD Life Science) which was mounted on a portable stand. The device was positioned 15-30 cm above the transplanted kidney, with the speckle lens aligned to the graft surface. Automatic focusing was applied to optimize image clarity, and images of the upper pole of the kidney were captured within a 15 × 15 cm field of view. 60 seconds of microcirculation imaging and perfusion curves were recorded at the upper pole of the kidney after reperfusion and immediately prior to abdominal closure (Figure 1). Perfusion Index (PI) was calculated using the software of the RFLSI-ZW LSCI system, which was closely related to the product of mean erythrocyte flow velocity and concentration within the tissue.
Locations (1)
The Second Affiliated Hospital of Chongqing Medical University
Chongqing, Chongqing Municipality, China