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Adapted Cardiopulmonary Resuscitation Study
Sponsor: Johannes Kepler University of Linz
Summary
The goal of this controlled single centre RCT is to compare frequency rates concerning return of spontaneous circulation (ROSC) in prehospital cardiac arrest. Two different algorithms (control-and interventiongroup) of advanced cardiac life support will be used to treat patients. In patients over 18 years suffering from cardiac arrest. The main question aims to answer if the frequency of ROSC differs between the groups receiving either the new Advanced Life Support (ALS) algorithm, or standard treatment. Researchers will compare the new algorithm to the standard care algorithm to see if there is a difference . Participants will be randomized to treatment on scene. The controlgroup will receive ALS standard treatment as performed in local protocols. The intervention group will receive a modified treatment including: * thorax compression via mechanical device (LUCAS 3) * head up Cardiopulmonary Resuscitation (cpr) * use of an impendance threshold device (ITD) module * arterial line placement * continuous epinephrin infusion via infusion pump * double sequence defibrillation
Official title: Adapted CPR (aCPR) a Bundle of Measures for Out of Hospital Cardiac Arrest (OHCA) Patients
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
216
Start Date
2026-01-28
Completion Date
2029-03-28
Last Updated
2026-08-10
Healthy Volunteers
No
Conditions
Interventions
aCPR algorithm
* thorax compression via mechanical device (LUCAS 3) * head up cpr * use of an ITD module * arterial line placement * continuous epinephrin infusion via infusion pump * double sequence defibrillation
ERC ALS 2025
Placement of an IV line, placement of a supraglottic airway device or endotracheal intubation. Optional use of an intraosseus acces
Locations (1)
Kepler University Hospital
Linz, Upper Austria, Austria