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RECRUITING
NCT07754656
NA

Adapted Cardiopulmonary Resuscitation Study

Sponsor: Johannes Kepler University of Linz

View on ClinicalTrials.gov

Summary

The goal of this controlled single centre RCT is to compare frequency rates concerning return of spontaneous circulation (ROSC) in prehospital cardiac arrest. Two different algorithms (control-and interventiongroup) of advanced cardiac life support will be used to treat patients. In patients over 18 years suffering from cardiac arrest. The main question aims to answer if the frequency of ROSC differs between the groups receiving either the new Advanced Life Support (ALS) algorithm, or standard treatment. Researchers will compare the new algorithm to the standard care algorithm to see if there is a difference . Participants will be randomized to treatment on scene. The controlgroup will receive ALS standard treatment as performed in local protocols. The intervention group will receive a modified treatment including: * thorax compression via mechanical device (LUCAS 3) * head up Cardiopulmonary Resuscitation (cpr) * use of an impendance threshold device (ITD) module * arterial line placement * continuous epinephrin infusion via infusion pump * double sequence defibrillation

Official title: Adapted CPR (aCPR) a Bundle of Measures for Out of Hospital Cardiac Arrest (OHCA) Patients

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

216

Start Date

2026-01-28

Completion Date

2029-03-28

Last Updated

2026-08-10

Healthy Volunteers

No

Interventions

PROCEDURE

aCPR algorithm

* thorax compression via mechanical device (LUCAS 3) * head up cpr * use of an ITD module * arterial line placement * continuous epinephrin infusion via infusion pump * double sequence defibrillation

PROCEDURE

ERC ALS 2025

Placement of an IV line, placement of a supraglottic airway device or endotracheal intubation. Optional use of an intraosseus acces

Locations (1)

Kepler University Hospital

Linz, Upper Austria, Austria