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COMPLETED
NCT07755566
NA

Effect of Papilozumib Oral on Vaginal and Intestinal Microbiota in HPV-Positive Women

Sponsor: Hifas da Terra S.L.

View on ClinicalTrials.gov

Summary

This open-label, single-group study evaluated the effects of a 3-month oral synbiotic dietary supplement on vaginal and intestinal microbiota in women with a positive human papillomavirus (HPV) test. Vaginal and intestinal microbiota were assessed at baseline and after 3 months of supplementation. Secondary assessments included HPV clearance, vaginal health, safety and tolerability, and treatment adherence.

Official title: Open-Label Clinical Trial to Evaluate the Effect of the Mico HPV Synbiotic Dietary Supplement on Vaginal and Intestinal Microbiota in HPV-Positive Patients

Key Details

Gender

FEMALE

Age Range

30 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

21

Start Date

2023-05-05

Completion Date

2024-05-30

Last Updated

2026-08-10

Healthy Volunteers

No

Interventions

DIETARY_SUPPLEMENT

Papilozumib

Oral synbiotic dietary supplement containing extracts of Hericium erinaceus, Cordyceps sinensis, and Ganoderma lucidum, together with Saccharomyces cerevisiae, Lactobacillus rhamnosus, vitamins C, E, D3 and A, zinc, selenium, and acerola extract. Participants received three capsules daily for 3 months: two capsules in the morning while fasting and one capsule before the midday meal.

Locations (1)

Instituto Palacios, Salud y Medicina de la Mujer

Madrid, Madrid, Spain