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Effects of Intermittent Fasting Variations on Nutrigenomic Profile, Metabolic Parameters, Inflammation, and Body Composition in Prediabetic Patients
Sponsor: Muhammad Aron Pase
Summary
Prediabetes is a metabolic condition associated with increased risk of type 2 diabetes and cardiovascular disease. Intermittent fasting (IF) has emerged as a potential dietary intervention to improve metabolic health, yet comparative evidence among different IF patterns remains limited. This randomized controlled trial aims to evaluate the effects of three intermittent fasting regimens-5:2 fasting, alternate-day fasting, and time-restricted feeding-compared with a control diet on metabolic parameters, inflammatory markers, body composition, and nutrigenomic profiles in adults with prediabetes.
Key Details
Gender
All
Age Range
25 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
120
Start Date
2026-08-01
Completion Date
2026-10-31
Last Updated
2026-08-10
Healthy Volunteers
No
Conditions
Interventions
Diet
Intermittent Fasting
Locations (1)
Department of Internal Medicine - Endocrinology Division, Faculty of Medicine, Universitas Sumatera Utara / RSUP H. Adam Malik Medan
Medan, North Sumatera, Indonesia