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Buerger's Exercises and Proprioceptive Drills on Postural Stability and Foot Perfusion in Elderly Patients With Chemotherapy
Sponsor: South Valley University
Summary
Chemotherapy-induced peripheral neuropathy (CIPN) is a common, dose-limiting side effect of neurotoxic chemotherapy agents, characterized by sensory loss, impaired proprioception, and muscle weakness, predominantly affecting the lower limbs. These impairments significantly contribute to postural instability and increase fall risk in elderly patients. Additionally, CIPN-associated microvascular changes can compromise peripheral circulation, further exacerbating neuromotor dysfunction and balance deficits. While pharmacological options for CIPN are limited and often inadequate, exercise-based interventions have shown promise in mitigating functional impairments. Buerger's exercises, a vascular stimulation technique, are known to enhance peripheral blood flow, whereas proprioceptive drills can improve neuromuscular coordination and postural control. However, their combined effect on both postural stability and foot perfusion in elderly patients with CIPN has not been systematically studied.
Official title: Combined Effect of Buerger's Exercises and Proprioceptive Drills on Postural Stability and Foot Perfusion in Elderly Patients With Chemotherapy-Induced Peripheral Neuropathy Randomized Controlled Trial
Key Details
Gender
All
Age Range
65 Years - Any
Study Type
INTERVENTIONAL
Enrollment
70
Start Date
2026-07-25
Completion Date
2026-12-01
Last Updated
2026-08-10
Healthy Volunteers
Yes
Interventions
Buerger's Exercises
Buerger's Exercises + Proprioceptive Drills, 3 times/week for 8 weeks: * Buerger's Exercises: * Leg elevation at 45° for 2 min until blanching * Dependent sitting for 3 min until hyperemia * Supine rest for 5 min * 3 cycles per session * Proprioceptive Drills: * Single-leg stance * Tandem stance/walking * Heel-to-toe walking * Anterior-posterior and lateral weight shifts * Mini-squats on foam * Ankle alphabet * Progressively increased difficulty Sessions supervised by trained physiotherapists.