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NOT YET RECRUITING
NCT07756112
NA

Dynamics of Wound Healing in Patients With Obesity

Sponsor: University of Iowa

View on ClinicalTrials.gov

Summary

Healing after dental surgery can vary from person to person. This study is being done to understand how body weight (obesity vs. normal weight) may affect healing after tissue is removed from the roof of the mouth during a gum graft procedure. The study will also evaluate whether a healing material made from a participant's own blood, called platelet-rich fibrin (PRF), is comparable in quantity and quality to the standard-of-care collagen plug. First, participants will be classified into obese or normal weight groups. Next, participants will be randomized to receive either collagen plug or platelet-rich fibrin clot during their surgical procedure Then, participants will return for 4 visits up to 30 days from the surgery visit.

Official title: Temporal Dynamics of Palatal Wound Healing With and Without Adjunctive Biologics in Patients With Obesity

Key Details

Gender

All

Age Range

18 Years - 70 Years

Study Type

INTERVENTIONAL

Enrollment

104

Start Date

2026-08

Completion Date

2029-08

Last Updated

2026-08-10

Healthy Volunteers

No

Conditions

Interventions

PROCEDURE

Collagen Plug (standard of care)

Collagen Plug (standard of care)

PROCEDURE

Platelet-Rich Fibrin Clot

Platelet-Rich Fibrin Clot is placed on wound

Locations (1)

University of Iowa College of Dentistry and Dental Clinics

Iowa City, Iowa, United States