Clinical Research Directory

Inclusion Criteria: * Healthy males aged 20-55 * Currently active (engaged in moderate to vigorous activity at least 2-days per week as defined by the American College of Sports Medicine Guidelines) * Estimated VO2 max greater than the 40th percentile of the population norm for age (assessed via ACSM guidelines, 2014). The VO2 max estimation at screening will be obtained by following a non-exercise regression model validated and described by Bradshaw et al. (2005). * Able to read and write in English * During the study, agree not to take any other supplements that may increase muscle strength or endurance (e.g. protein formulas, creatine, amino acids, tyrosol or stimulants other than caffeine). * During the study, subjects will not deviate from their normal daily routine unless it conflicts with study criteria. This includes maintaining their present workout routine and diet, without substantial changes. Exclusion Criteria: * Known diagnosis of any cardiovascular, metabolic, endocrine, or renal disease * Uncontrolled stage II hypertension or higher * Recent musculoskeletal injury (\<3-months) * Recent orthopaedic surgery (\<12-months) * History of or current malignancy * Previous gastrointestinal surgery within the past 12 months * Regular smoker * Regular drinker (\>14 drinks per week) * Current use (within the past 5 weeks) of creatine supplements * Current use (within past 3 months) of Tyrosol supplementation * Current use of dietary supplements that may enhance mitochondrial function, muscle hypertrophy, or muscle strength (e.g. protein formulas, creatine, amino acids, tyrosol, etc.). * Current use of prescription medications that may influence adaptation to exercise (hormone therapies, peptides, etc.)