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Photodynamic Therapy For Onychomycosis
Sponsor: The University of Texas Health Science Center, Houston
Summary
The purpose of this study is clinical and mycological clearance of onychomycosis using photodynamic therapy (PDT) with aminolevulinic acid (ALA) 10% gel at 6 months, 3 months, 9 months and 12 months
Official title: Photodynamic Therapy For Onychomycosis: An Open Label Study
Key Details
Gender
All
Age Range
18 Years - 100 Years
Study Type
INTERVENTIONAL
Enrollment
5
Start Date
2026-08-10
Completion Date
2027-12-31
Last Updated
2026-08-11
Healthy Volunteers
No
Conditions
Interventions
ALA 10% gel
ALA 10% gel will be applied under occlusion for 3 hours before PDT
PDT
Participants will have illumination on the affected nail with RhodoLED® XL 635 nm red light at 37 J/cm² at 5 inches for 13.5 minutes.
Urea
Participants will have 20% urea applied to affected nail daily for 2 weeks before start of treatment
Locations (3)
Arlington Center for Dermatology
Arlington, Texas, United States
Houston Skin
Houston, Texas, United States
Houston Skin
Webster, Texas, United States