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NOT YET RECRUITING
NCT07757373
PHASE4

Romosozumab Versus Denosumab In Glucocorticoid-induced Osteoporosis: An Extended Observation Of a Randomized Controlled Trail At 6 Years

Sponsor: Tuen Mun Hospital

View on ClinicalTrials.gov

Summary

This is an extended observation study of a RCT comparing the efficacy of romorozumab and denosumab in high-risk patients using long-term glucocorticoids. In the romosozumab arm, patients were shifted to denosumab after the first year. The denosumab arm of patients were continued on denosumab. This study aims to look at the bone mineral density changes in both groups of patients after 6 years.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

54

Start Date

2026-09-01

Completion Date

2027-12-01

Last Updated

2026-08-11

Healthy Volunteers

No

Interventions

DRUG

Romosozumab

romosozumab for 12 months, followed by denosumab

DRUG

Denosumab

demonsumab

Locations (1)

Tuen Mun Hospital

Hong Kong, Hong Kong