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Romosozumab Versus Denosumab In Glucocorticoid-induced Osteoporosis: An Extended Observation Of a Randomized Controlled Trail At 6 Years
Sponsor: Tuen Mun Hospital
Summary
This is an extended observation study of a RCT comparing the efficacy of romorozumab and denosumab in high-risk patients using long-term glucocorticoids. In the romosozumab arm, patients were shifted to denosumab after the first year. The denosumab arm of patients were continued on denosumab. This study aims to look at the bone mineral density changes in both groups of patients after 6 years.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
54
Start Date
2026-09-01
Completion Date
2027-12-01
Last Updated
2026-08-11
Healthy Volunteers
No
Interventions
Romosozumab
romosozumab for 12 months, followed by denosumab
Denosumab
demonsumab
Locations (1)
Tuen Mun Hospital
Hong Kong, Hong Kong