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Exposure Therapy for Reactivity to Symptoms
Sponsor: Region Stockholm
Summary
It is unclear to what degree systematic exposure exercises contribute to the overall effects of exposure therapy (exposure and response prevention). This trial recruits individuals with high somatic symptom burden or reactivity to symptoms who, based on previous work, are likely to benefit specifically from exposure therapy. The aim of the study is to evaluate to what degree the effect of exposure therapy for this group is driven by the addition of structured exposure exercises to response prevention. This will be evaluated on the basis of a randomized controlled trial (N=360) where participants are enrolled either in response prevention (n=180), or exposure and response prevention (n=180). Primary outcome will be the between-group differences in the reduction in reactivity to symptoms, as measured week-by-week using the somatic symptom disorder B-criteria scale (SSD-12). Results from this project will be informative for exposure-based and various multicomponent behavioral treatments for individuals with persistent physical symptoms worldwide.
Official title: Randomized Controlled Dismantling Trial of Exposure Therapy for Reactivity to Symptoms
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
360
Start Date
2026-09
Completion Date
2031-12
Last Updated
2026-08-11
Healthy Volunteers
No
Conditions
Interventions
Planned, systematic, exposure exercises
Exposure exercises, planned on the basis of functional analysis. Participants are encouraged to evaluate the relevance of-, and if so work continuously with-, interceptive, in vivo, and imaginal exposure exercises which are planned at specific timepoints.
Response prevention
Response prevention, planned on the basis of functional analysis. Participants make a plan to reduce presumably negatively reinforced behavior contingent on somatic symptoms and distress related to somatic symptoms.
Locations (1)
Liljeholmen University Primary Health Care Centre
Stockholm, Sweden