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NOT YET RECRUITING
NCT07760051
NA

Effects of Agent-assisted, LLM-assisted and Traditional Workflows on Diagnosis and Management Planning at Admission

Sponsor: Second Affiliated Hospital, Zhejiang University, School of Medicine

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to evaluate whether AI-assisted workflows improve physicians' admission diagnosis and management planning performance on standardized simulated inpatient cases, among practicing internal medicine and surgery physicians across all seniority levels and across three tiers of the Chinese healthcare system. The main questions it aims to answer are: * Does the Agent-assisted workflow yield better structured admission diagnosis and management planning scores than standalone LLM assistance? * Does the Agent-assisted workflow outperform the traditional workflow without AI tools? Researchers will compare three parallel groups (traditional workflow group, LLM-assisted group, Agent-assisted group) to determine whether the Agent tool can improve diagnostic accuracy and efficiency. Participants will: * Be recruited from 15 hospitals in China and participate remotely under video proctoring * Be randomly assigned to one of the three fixed workflows, with randomization stratified by hospital tier, specialty and seniority * Complete 6 anonymized simulated HIS admission cases within one hour * Submit structured answers for each case covering principal diagnosis, secondary diagnoses, differential diagnoses, diagnostic justification, next diagnostic or therapeutic steps, consultation and referral decisions, and diagnostic confidence * Have their operation logs and time consumption recorded automatically by the study platform

Official title: Effects of Agent-assisted, LLM-assisted and Traditional Workflows on Diagnosis and Management Planning at Admission: A Randomized Controlled Study

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

180

Start Date

2026-08

Completion Date

2026-12

Last Updated

2026-08-18

Healthy Volunteers

Yes

Interventions

OTHER

Agent-assisted workflow

Conventional resources (pre-admission clinical record, search engines) plus an in-system Agent entry that automatically reads the full record and report images, produces a structured summary with source-text tracing, and supports multi-turn Q\&A and one-click editable drafts.

OTHER

LLM-assisted workflow

Conventional resources plus an in-system multi-turn AI dialogue entry. The AI does not automatically read the record; participants paste text or send partial screenshots.

OTHER

Traditional Workflow

Conventional resources only: the pre-admission clinical record, standard search engines. No AI assistance.

Locations (1)

2nd Affiliated Hospital, School of Medicine, Zhejiang University

Hangzhou, Zhejiang, China