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The Use of Advanced Platelet-rich Fibrin in Mandibular Third Molar Surgery
Sponsor: University of Copenhagen
Summary
The purpose of the study is to quantify the levels of platelets and inflammatory markers in A-PRF from a standard venous whole blood sample, and to evaluate the effect of A-PRF on postoperative discomfort and complications following surgical removal of M3. The study will be prospective and include 60 patients referred to Specialtandlægerne Vestergade for surgical removal of one M3. It is expected that the study will contribute with important information on the impact of A-PRF on postoperative sequelae and complications following surgical removal of mandibular third molars.
Official title: The Use of Advanced Platelet-rich Fibrin in Mandibular Third Molar Surgery. Levels of Platelets, Leucocytes, Inflammatory Biomarkers and the Effect on Postoperative Discomfort and Complications.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
60
Start Date
2024-10-01
Completion Date
2025-01-31
Last Updated
2026-08-12
Healthy Volunteers
Yes
Conditions
Interventions
Third molar
Evaluate the level of thrombocytes and growth factors in A-PRF and whole blood sample
Locations (1)
University of Copenhagen
Copenhagen, Denmark