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Comparsion of Effect of PRP,PDE5 Inhibitor in Treatment of Erectile Dysfunction
Sponsor: Ain Shams University
Summary
Erectile dysfunction (ED) is defined as the inability to attain and/or maintain penile erection sufficient for satisfactory sexual performance.Erectile dysfunction (ED) is one of the commonest disorders in adult males and affects 12-19% of men of reproductive age.Erectile dysfunction can be due to vasculogenic, neurogenic, hormonal, veno-occlusive, psychogenic and/or pharmacogenic factors. PRP is autologous plasma that has a platelet concentration above the concentrations typically found in whole blood and is derived from the patient's own blood (autologous) through a process of centrifugation. PDE5Is inhibit the enzyme phosphodiesterase-5 (PDE-5) leading to dilatation of the penile arteries leads to a more prolonged erection.
Official title: Comparison Between The Effect of Intracavernosal Injection of Platelet-Rich Plasma as a Single Agent vs Daily Oral 5 Phosphodiesterase Inhibitor Intake as a Single Agent Vs Combination In Improving of Erectile Dysfunction
Key Details
Gender
MALE
Age Range
30 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
75
Start Date
2024-01-15
Completion Date
2024-10-01
Last Updated
2026-08-12
Healthy Volunteers
No
Conditions
Interventions
Tadalafil 5mg
To compare between Intra Cavernous Injection of Platelet Rich Plasma (PRP) as a single agent , 5 PDE inhibitor as a single agent vs combined effect of two agent to achieve an efficient therapy with less cost for the treatment of Erectile Dysfunction.
Locations (1)
Ain Shams University Hospital
Cairo, Abbasia, Egypt