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NCT07761832

Hemoglobin Trends as a Predictor of Outcomes in Critically Ill Patients (The TRENT-ICU Study)

Sponsor: Hospital H+ Queretaro

View on ClinicalTrials.gov

Summary

The goal of this observational study is to evaluate if early absolute hemoglobin decline (during the first 24 hours of admission) can predict prolonged intensive care unit stay (8 days or more) and in-hospital mortality in critically ill adult patients. The main questions it aims to answer are: Does absolute hemoglobin decline during the first 24 hours of admission independently predict prolonged intensive care unit stay in critically ill adult patients? Does absolute hemoglobin decline during the first 24 hours of admission independently predict in-hospital mortality in critically ill adult patients? Participants will: Have their routine clinical and laboratory data reviewed retrospectively from their electronic health records (including baseline hemoglobin and a second hemoglobin determination approximately 24 hours after admission). No additional interventions or extra blood draws will be performed beyond routine clinical care.

Official title: The TRENT-ICU Study (Transfusion Threshold Based on Hemoglobin Trends): Hemoglobin Drop Rate as a Predictor of Adverse Clinical Outcomes in Critically Ill Patients

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

128

Start Date

2026-07-31

Completion Date

2026-07-31

Last Updated

2026-08-12

Healthy Volunteers

No

Interventions

OTHER

Early Absolute Hemoglobin Decline

Measurement of the absolute difference in hemoglobin concentration (g/dL) between baseline ICU admission and approximately 24 hours post-admission. Data was collected retrospectively from electronic health records.

Locations (1)

Hospital H+ Querétaro, Santiago de Querétaro, Querétaro

Querétaro City, Querétaro, Mexico