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Perioperative HALP and Surgical Outcomes
Sponsor: Istanbul Saglik Bilimleri University
Summary
Esophagectomy is associated with substantial postoperative morbidity despite advances in perioperative care. The Hemoglobin, Albumin, Lymphocyte, and Platelet (HALP) score has been proposed as a composite biomarker reflecting nutritional, inflammatory, and immune status; however, its perioperative behavior and clinical significance after esophagectomy remain unclear. This retrospective cohort study evaluates perioperative changes in HALP and examines the associations of preoperative, postoperative day 1, and postoperative day 7 HALP measurements with postoperative complications, including overall and major complications, anastomotic leakage, ICU readmission, and length of hospital stay. The study aims to clarify the potential role of perioperative HALP as a marker of postoperative recovery and adverse clinical outcomes following esophagectomy.
Official title: Perioperative Changes in Hemoglobin, Albumin, Lymphocyte, and Platelet (HALP) Score and Postoperative Outcomes After Esophagectomy
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
131
Start Date
2026-06-10
Completion Date
2026-07-22
Last Updated
2026-08-13
Healthy Volunteers
No
Conditions
Interventions
Perioperative HALP Score Assessment
Assessment of the Hemoglobin, Albumin, Lymphocyte, and Platelet (HALP) score using routinely collected laboratory measurements obtained preoperatively and on postoperative days 1 and 7. No intervention or treatment was assigned as part of the study.
Locations (1)
Basaksehir Cam and Sakura City Hospital
Istanbul, Istanbul, Turkey (Türkiye)