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Autologous Nanofat Injection for Treatment of Stable Vitiligo
Sponsor: Benha University
Summary
This randomized, split-site, within-participant controlled clinical study evaluated the efficacy and safety of a single session of autologous nanofat injection as an adjunct to narrowband ultraviolet B (NB-UVB) phototherapy in 20 adult patients with stable vitiligo. In each participant, one vitiligo site received autologous nanofat injection followed by NB-UVB phototherapy three times weekly for 3 months, while a comparable site received NB-UVB phototherapy alone. Treatment response was assessed by standardized photography performed by a blinded dermatologist, with evaluation of the onset and percentage of repigmentation, patient satisfaction, and treatment-related adverse effects.
Official title: Evaluation of The Effect of Autologous Nanofat Injection in the Treatment of Vitiligo
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2024-04-01
Completion Date
2026-03-01
Last Updated
2026-08-13
Healthy Volunteers
No
Conditions
Interventions
Autologous Nanofat Injection
A single session of autologous nanofat injection was performed in the randomly assigned vitiligo site. Nanofat was prepared from the participant's own adipose tissue according to the study protocol and injected into the selected vitiligo lesion.
NB-UVB Phototherapy
Narrowband ultraviolet B (NB-UVB) phototherapy was administered to both the nanofat-treated and control sites three times weekly for 3 months according to the study protocol.
Locations (1)
Benha faculty of medicine hospital
Banhā, Qaluybia, Egypt