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Ultrasonographic Evaluation of Cosmetic Keratolytic Treatment of Foot Calluses and Corns
Sponsor: Wroclaw University of Health and Sport Sciences
Summary
This prospective, non-randomized, controlled study evaluated the efficacy of a topical cosmetic keratolytic preparation (serum and cream containing urea, salicylic acid, and collagen) in reducing the thickness and associated pain of hyperkeratotic foot lesions (calluses and corns). High-frequency ultrasonography (18 MHz) was used for precise, quantitative measurement of lesion thickness before and after a two-month intervention. Participants were allocated to four parallel groups (treated calluses, untreated callus controls, treated corns, and untreated corn controls).
Official title: Ultrasonographic Evaluation of Cosmetic Keratolytic Treatment of Hyperkeratotic Foot Lesions: A Prospective, Non-randomized, Controlled, Comparative Study of Calluses and Corns
Key Details
Gender
FEMALE
Age Range
35 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
124
Start Date
2020-02-01
Completion Date
2026-05-01
Last Updated
2026-08-14
Healthy Volunteers
No
Interventions
Topical Keratolytic Cosmetic (Serum + Cream)
Application of 2 mL serum followed by 2 mL cream containing urea, salicylic acid, and collagen, massaged into the hyperkeratotic lesion for 2 minutes, twice daily (morning and evening) for 2 months
Locations (1)
OSTEON Clinic
Swidnica, Poland