Clinical Research Directory
Browse clinical research sites, groups, and studies.
Mediterranean and Low-Histamine Diets for Pediatric Chronic Spontaneous Urticaria
Sponsor: Saglik Bilimleri Universitesi
Summary
Chronic spontaneous urticaria (CSU) is a chronic inflammatory skin disease that can substantially impair quality of life in children and adolescents. Pharmacological treatment may not adequately control symptoms in all patients, increasing interest in dietary interventions. This randomized controlled trial aims to compare the effects of a Mediterranean diet and a low-histamine diet, in addition to standard medical treatment, on disease activity, disease control, and quality of life in pediatric patients aged 12-18 years with chronic spontaneous urticaria. Participants will be allocated to one of three groups: standard treatment alone, standard treatment plus a low-histamine diet, or standard treatment plus a Mediterranean diet. The dietary intervention will last four weeks, with follow-up through eight weeks.
Official title: The Effects of the Mediterranean and Low-Histamine Diets on Disease Severity in Pediatric Chronic Spontaneous Urticaria
Key Details
Gender
All
Age Range
12 Years - 18 Years
Study Type
INTERVENTIONAL
Enrollment
63
Start Date
2025-11-23
Completion Date
2027-01-15
Last Updated
2026-08-14
Healthy Volunteers
No
Conditions
Interventions
Low-Histamine Diet
Participants assigned to this intervention will receive a low-histamine diet in addition to standard medical treatment for 4 weeks.
Mediterranean Diet
Participants assigned to this intervention will receive a Mediterranean diet in addition to standard medical treatment for 4 weeks.
Locations (1)
T.C. İstanbul Prof. Dr. Cemil Taşcıoğlu Şehir Hastanesi
Istanbul, Turkey (Türkiye)