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Pain Phenotypes in Individuals With Chronic Low Back Pain
Sponsor: Kutahya Health Sciences University
Summary
This observational cross-sectional study aims to determine pain phenotypes in individuals with chronic low back pain (CLBP). Participants will be classified according to a mechanism-based clinical pain phenotyping algorithm as having nociceptive, neuropathic, nociplastic, or mixed pain. Clinical history, quantitative sensory assessment, pain characteristics and distribution, central sensitization-related symptoms, disability, health-related quality of life, and pain catastrophizing will be assessed. In addition, the intra-rater and inter-rater reliability of the pain phenotyping algorithm will be investigated, and the clinical characteristics of different pain phenotypes will be compared.
Official title: Pain Phenotypes in Chronic Low Back Pain Based on IASP Criteria
Key Details
Gender
All
Age Range
18 Years - 70 Years
Study Type
OBSERVATIONAL
Enrollment
80
Start Date
2025-01-02
Completion Date
2026-12-31
Last Updated
2026-08-14
Healthy Volunteers
No
Conditions
Interventions
Pain classification method
A current clinical algorithm will be used to determine the predominant type of pain in individuals with clip. The classification to diagnose nociceptive, neuropathic and nociplastic pain will based on a recent method developed by Nijs et al. This method consists of seven steps in total. These steps question the following, respectively: duration of pain, pain distribution, presence of nociceptive pain, presence of neuropathic pain, phenomenon of hypersensitivity, presence of hypersensitization and presence of specific comorbidity. Besides, inter-rater and intra-rater reliability of pain classification algorithm will be determined by two independent researchers.
Locations (1)
Kutahya Health Sciences University Physical Medicine and Rehabilitation Department
Kütahya, Türkiye, Turkey (Türkiye)