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Mapping the Neural Circuits of Depression and Anxiety Using Personalized, Accelerated TMS and Deep Phenotyping
Sponsor: National University Hospital, Singapore
Summary
This proposal seeks to carry out a double-blinded, randomized, comparative study that investigates neurobehavioral changes induced by personalized, anxiosomatic and dysphoric network guided accelerated intermittent-theta burst (iTBS) using dense functional Magnetic Resonance Imaging (fMRI) sampling in participants with treatment-resistant depression (TRD) and moderate/high levels of anxiety.
Key Details
Gender
All
Age Range
21 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
36
Start Date
2026-09-01
Completion Date
2029-12-31
Last Updated
2026-08-14
Healthy Volunteers
No
Conditions
Interventions
Individualized connectome-guided accelerated iTBS
Magpro X100, Axilium Cobot, Localite Camera
Locations (1)
National University Hospital, Singapore
Singapore, Singapore