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Magnesium Oxide and Letrozole Versus Letrozole Alone on Ovarian Response in Insulin Resistant PCOS
Sponsor: Bangladesh Medical University
Summary
Does pretreatment with magnesium oxide followed by letrozole increase ovulation rate? What medical problems do participants have when taking drug magnesium oxide and letrozole? Researchers will compare magnesium oxide and letrozole to letrozole alone to see pretreatment with magnesium oxide followed by letrozole works better as ovulation induction. Experimental group will receive magnesium oxide and letrozole alone. Comparator group will receive letrozole alone.
Official title: Effect of Pretreatment With Magnesium Oxide Followed by Letrozole on Ovarian Response in Subfertile Women With Insulin Resistant Polycystic Ovarian Syndrome in Comparison to Letrozole Alone
Key Details
Gender
FEMALE
Age Range
18 Years - 35 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2025-06-01
Completion Date
2026-05-28
Last Updated
2026-08-14
Healthy Volunteers
No
Conditions
Interventions
Experimental drug: Magnesium oxide (365 mg)
Participants will receive tab magnesium oxide 365mg twice daily for 3months followed by tab letrozole 2.5mg 3 tablets daily at night from 2nd to 6th day of menstruation.
Letrozole 2.5mg
Participants will receive 2.5mg of letrozole, 3 tablets at night from 2nd to 6th day of menstruation
Locations (1)
Bangladesh Medical University
Dhaka, Shahbag, Bangladesh