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RECRUITING
NCT07767084
NA

Influence of Sealer Composition on Post-Endodontic Pain

Sponsor: Minia University

View on ClinicalTrials.gov

Summary

Postoperative pain (PP) is one of the most common and clinically significant complications following endodontic therapy, occurring shortly after treatment and potentially lasting from a few hours to several days, thereby compromising the patient's quality of life. The incidence of PP varies widely in the literature, ranging from 1.7% to 70%, with some studies reporting values up to 80% within the first 24 hours, gradually decreasing over a week.

Official title: Influence of Sealer Composition on Post-Endodontic Pain: A Prospective Comparative Analysis of Three Root Canal Sealers

Key Details

Gender

All

Age Range

18 Years - 45 Years

Study Type

INTERVENTIONAL

Enrollment

66

Start Date

2026-04-14

Completion Date

2027-04-14

Last Updated

2026-08-17

Healthy Volunteers

No

Interventions

PROCEDURE

Calcium Hydroxide-based Sealer

to evaluate and compare the incidence and intensity of postoperative pain following single-visit root canal treatment using three different root canal sealers-calcium hydroxide-based, calcium silicate-based (bioceramic), and epoxy resin-based sealers-in patients with single-rooted teeth, in order to determine the effect of sealer type on patient comfort and analgesic consumption.

Locations (1)

Endodontics Department Faculty of Dentistry

Minya, Egypt