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Long-term Safety of UAS-assisted vs Sheathless RIRS in Non-prestented Patients
Sponsor: Al-Azhar University
Summary
This retrospective comparative cohort study will include adult patients who underwent primary RIRS for renal stones ≤20 mm at Al-Azhar University Hospitals between January 2020 and December 2025. Patients will be classified by whether a ureteral access sheath (UAS) was used during the index RIRS, and all eligible patients will be invited for active long-term follow-up (minimum 12 months) to assess the composite outcome of delayed ipsilateral ureteral stricture or new/progressive ipsilateral hydronephrosis and other safety and efficacy outcomes. Propensity-score methods and adjusted regression analyses will be used to control confounding.
Official title: Long-Term Safety Outcomes of Ureteral Access Sheath-Assisted Versus Sheathless Retrograde Intrarenal Surgery for Renal Stones ≤20 mm in Non-Prestented Patients: A Retrospective Comparative Cohort Study With Active Follow-up
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
1200
Start Date
2026-08-20
Completion Date
2027-12-25
Last Updated
2026-08-17
Healthy Volunteers
No
Conditions
Interventions
Ureteral access sheath-assisted RIRS
Retrograde intrarenal surgery (RIRS) performed with placement of a ureteral access sheath during the initial procedure. Details recorded: sheath diameter (Fr), length, manufacturer/model, insertion success, number of insertion attempts, need for ureteral dilation, intraoperative findings.
Sheathless RIRS
RIRS performed without placement of a ureteral access sheath. Details recorded: guidewire use, ureteral dilation, access difficulty, intraoperative findings.
Locations (1)
Department of Urology, Al-Hussein and Sayed Galal University Hospitals, Al-Azhar University
Cairo, Egypt