Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
NOT YET RECRUITING
NCT07767773

Long-term Safety of UAS-assisted vs Sheathless RIRS in Non-prestented Patients

Sponsor: Al-Azhar University

View on ClinicalTrials.gov

Summary

This retrospective comparative cohort study will include adult patients who underwent primary RIRS for renal stones ≤20 mm at Al-Azhar University Hospitals between January 2020 and December 2025. Patients will be classified by whether a ureteral access sheath (UAS) was used during the index RIRS, and all eligible patients will be invited for active long-term follow-up (minimum 12 months) to assess the composite outcome of delayed ipsilateral ureteral stricture or new/progressive ipsilateral hydronephrosis and other safety and efficacy outcomes. Propensity-score methods and adjusted regression analyses will be used to control confounding.

Official title: Long-Term Safety Outcomes of Ureteral Access Sheath-Assisted Versus Sheathless Retrograde Intrarenal Surgery for Renal Stones ≤20 mm in Non-Prestented Patients: A Retrospective Comparative Cohort Study With Active Follow-up

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

1200

Start Date

2026-08-20

Completion Date

2027-12-25

Last Updated

2026-08-17

Healthy Volunteers

No

Interventions

PROCEDURE

Ureteral access sheath-assisted RIRS

Retrograde intrarenal surgery (RIRS) performed with placement of a ureteral access sheath during the initial procedure. Details recorded: sheath diameter (Fr), length, manufacturer/model, insertion success, number of insertion attempts, need for ureteral dilation, intraoperative findings.

PROCEDURE

Sheathless RIRS

RIRS performed without placement of a ureteral access sheath. Details recorded: guidewire use, ureteral dilation, access difficulty, intraoperative findings.

Locations (1)

Department of Urology, Al-Hussein and Sayed Galal University Hospitals, Al-Azhar University

Cairo, Egypt