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The Effect of L-Carnitine on Wound Healing in Patients With Diabetic Foot Ulcer.
Sponsor: Ain Shams University
Summary
Primary outcome: To evaluate the efficacy of L-Carnitine supplementation on length and depth ulcer size Secondary outcome: To investigate the effect of L-Carnitine supplements on: 1. Vascular endothelial growth factor (VEGF) 2. Inflammatory markers TNF-a (Tumor necrosis factor alpha). 3. Hemoglobin A1C (HbA1c) And Lipid profile (cholesterol, triglycerides, high-density Lipoprotein (HDL) and low-density lipoprotein (LDL)). 4. To assess the type and likelihood of any adverse drug reaction that can be related to L-Carnitine supplementation. 5. QOL (DIABETES 39)
Key Details
Gender
All
Age Range
30 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2026-09-01
Completion Date
2027-08-01
Last Updated
2026-08-17
Healthy Volunteers
No
Interventions
L- carnitine
oral L-carnitine
Locations (2)
Faculty of Pharmacy, Ain Shams University
Cairo, Cairo Governorate, Egypt
Faculty of Pharmacy, Ain Shams University
Cairo, Cairo Governorate, Egypt