Clinical Research Directory

Inclusion Criteria: * Have histologically or cytologically confirmed adenocarcinoma of the prostate * Have not received GnRH agonist or antagonist within the last 12 months * Planned for initiation of a GnRH agonist or antagonist or bilateral orchiectomy with an intended treatment duration of ≥ 6 months * Planned for initiation of radiation therapy to the prostate. * ECOG performance status of 0 or 1 * Ability to understand and the willingness to sign a written informed consent document * Baseline serum total testosterone level \> 230 ng/dL (the accepted threshold for testosterone supplementation) * Speak English -\>18 years of age Exclusion Criteria: * Has a known medical condition that makes the subject unable to participate in exercise testing (e.g. unrevascularized coronary artery disease, moderate/severe osteoarthritis, prior stroke, or other conditions) * Receiving or planned to receive other cancer therapy not included in Eligibility Criterion 3.1.3 (other than an antiandrogen during the first month of therapy) * The following populations will not be considered for inclusion on this trial.