Clinical Research Directory

Inclusion Criteria: * Patients with chronic kidney disease-associated pruritus (CKD-aP) undergoing maintenance hemodialysis twice weekly for more than 6 months and in a hemodynamically stable condition. * Aged 18 to 65 years old and willing to participate in the study. * Received standard therapy for at least 2 weeks and met the moderate to severe pruritus criteria based on Visual Analog Scale (VAS) score and 5-D Pruritus Scale. * Able to understand and comply with the study instructions/protocol. Exclusion Criteria: * Patients with active malignancy or active infection. * Patients with primary skin diseases, such as allergic dermatitis, irritant contact dermatitis, neurodermatitis, or psoriasis. * Patients with chronic liver disease or cholestatic disease. * Received phototherapy or acupuncture therapy within the last 1 week prior to study enrollment.