Clinical Research Directory
Browse clinical research sites, groups, and studies.
Cardiovascular Mortality Prediction in Maintenance Hemodialysis Patients
Sponsor: Huashan Hospital
Summary
This prospective, single-center observational cohort study evaluates cardiovascular mortality risk in adults receiving maintenance hemodialysis. During the first year after enrollment, four scheduled assessments are used to characterize demographic factors, dialysis treatment, medication use, routine laboratory measures, and the proportion of serum phosphate measurements within the protocol-defined target range. Participants are subsequently followed for cardiovascular mortality. The study evaluates factors associated with serum phosphate target achievement and develops a cardiovascular mortality prediction model in the overall cohort, with a prespecified subgroup analysis among participants who undergo parathyroidectomy. No treatment or procedure is assigned by the study investigators.
Official title: Development of a Mortality Prediction Model for Patients Receiving Maintenance Hemodialysis
Key Details
Gender
All
Age Range
18 Years - 85 Years
Study Type
OBSERVATIONAL
Enrollment
192
Start Date
2021-07-16
Completion Date
2022-04-21
Last Updated
2026-08-17
Healthy Volunteers
No
Interventions
One-Year Serum Phosphate Target Achievement Rate
The one-year serum phosphate target achievement rate is calculated as the number of evaluable scheduled serum phosphate measurements within the protocol-defined target range divided by the total number of evaluable scheduled measurements during the first year after enrollment. Four scheduled assessments are planned. Serum phosphate management is determined by routine clinical care and is not assigned by the study investigators.
Parathyroidectomy
Parathyroidectomy received as part of routine clinical care is recorded for prespecified subgroup analysis. The decision to perform parathyroidectomy is made by the treating clinical team and is not assigned by the study investigators.
Locations (1)
Huashan hospital, Fudan university
Shanghai, Shanghai Municipality, China