Clinical Research Directory

Inclusion Criteria: * Individuals diagnosed with piriformis syndrome * Presence of piriformis tenderness and sciatic symptoms * Aged between 18 and 65 years * Voluntary agreement to participate in the study * No history of lumbar, hip, knee, or ankle surgery within the last year * Ability to cooperate with the assessment and treatment procedures Exclusion Criteria: * Individuals younger than 18 years or older than 65 years * Presence of any musculoskeletal disorder affecting the lower extremity * Presence of neurological, cardiac, pulmonary, or orthopedic disorders preventing participation in exercise * Presence of neurological deficits (muscle strength loss) * History of radiotherapy to the lumbar or hip region * Absence from more than 20% of treatment sessions * Inability to comply with the study procedures (e.g., cognitive impairment, communication problems, severe psychiatric disorders) * Corticosteroid or PRP injection within the last 3 months * Participation in another physical therapy program within the last 3 months * Use of analgesic, anti-inflammatory, or muscle relaxant medications within the last 48-72 hours * Use of psychotropic medications that may affect muscle activation or nervous system responses (e.g., antidepressants, antipsychotics, sedatives)