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NOT YET RECRUITING
NCT07769970
NA

Restoring Independence With Stimulation-Enhanced Treatment for People With Functional Neurological Disorder

Sponsor: University of Auckland, New Zealand

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to test a new treatment for adults with walking problems due to Functional Neurological Disorder (FND). The main question the trial aims to answer is: \- Is stimulation-enhanced physical therapy an effective treatment for walking problems due to FND? Researchers will compare the stimulation-enhanced physical therapy to gold-standard physical therapy. Participants will: * Complete three in-person sessions on three consecutive days * Complete follow-up assessments by video call at 7 days, 30 days and 90 days after treatment

Official title: A Phase 3, Single-site, Assessor-blinded, Randomised Controlled Trial of Transcranial Magnetic Stimulation-Enhanced Treatment to Restore Movement Agency and Walking Independence in People With Functional Neurological Disorder

Key Details

Gender

All

Age Range

21 Years - Any

Study Type

INTERVENTIONAL

Enrollment

60

Start Date

2026-11

Completion Date

2030-04

Last Updated

2026-08-18

Healthy Volunteers

No

Interventions

COMBINATION_PRODUCT

Stimulation-Enhanced Physical Therapy

The intervention uses Transcranial Magnetic Stimulation (TMS) to activate the motor pathways from the primary motor cortex to affected lower limb muscles. This is followed by specialist physical therapy applying consensus recommendations for the treatment of movement symptoms due to FND. Key elements include distraction, momentum, and exploratory movement.

OTHER

Active Comparator

The active comparator uses structured goal-setting and movement imagery to prepare for physical therapy. This is followed by specialist physical therapy applying consensus recommendations for the treatment of movement symptoms due to FND. Key elements include distraction, momentum, and progressive movement retraining.

Locations (1)

Clinical Research Centre, Grafton Campus, University of Auckland

Auckland, Auckland, New Zealand