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COMPLETED
NCT07770087
NA

Effect of Metformin Gel on Guided Bone Regeneration Around Immediate Dental Implant at Posterior Maxillary Region

Sponsor: Al-Azhar University

View on ClinicalTrials.gov

Summary

To evaluate, by standardized radiographic follow-up, whether locally delivered 1% metformin gel improves bone healing around immediately placed dental implants augmented with GBR.

Official title: Evaluation of the Efficacy of Metformin Topical Application on Bone Healing Around Immediate Dental Implants

Key Details

Gender

All

Age Range

18 Years - 45 Years

Study Type

INTERVENTIONAL

Enrollment

12

Start Date

2022-11-01

Completion Date

2025-12-15

Last Updated

2026-08-18

Healthy Volunteers

Yes

Interventions

DRUG

Metformin 1% Topical Gel

A 1% metformin gel was topically applied around the dental implant at the time of immediate implant placement. The intervention was used in conjunction with guided bone regeneration using an alloplastic bone graft and collagen membrane in the posterior maxillary region.

PROCEDURE

immediate Dental Implant Placement With Guided Bone Regeneration

Immediate dental implant placement was performed following atraumatic extraction in the posterior maxillary region. Guided bone regeneration was performed using an alloplastic bone graft and collagen membrane around the implant. This procedure was performed in both study groups; participants in the control group received this protocol without topical metformin gel.

Locations (2)

Faculty of Dental Medicine, Al-Azhar University, Assiut Branch

Asyut, Assiut Governorate, Egypt

Department of Oral and Maxillofacial Surgery, Faculty of Dental Medicine, Al-Azhar University, Assiut Branch

Asyut, Egypt