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Assesment of Epidural Platelet-Rich Plasma (PRP) Injection During Uniportal Endoscopic Lumbar Disc Herniation Excision on Residual Neuropathies
Sponsor: GCS Ramsay Santé pour l'Enseignement et la Recherche
Summary
The aim of this study is to assess neuropathic pain in the lower limb at 6 months post-operation in patients who have undergone surgery for a lumbar disc herniation using single-port endoscopic discectomy combined with an epidural PRP injection. This study is based on the hypothesis that intraoperative epidural administration of PRP during discectomy may improve healing, reduce nerve inflammation and potentially minimise post-operative pain and complications. Participants will perform an epidural PRP injection and questionnaires as part of this research.
Official title: Assesment of Epidural Platelet-Rich Plasma (PRP) Injection During Uniportal Endoscopic Lumbar Disc Herniation Excision on Residual Neuropathies: An Exploratory Study.
Key Details
Gender
All
Age Range
18 Years - 55 Years
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2026-09-01
Completion Date
2028-09-01
Last Updated
2026-08-20
Healthy Volunteers
No
Conditions
Interventions
Uniportal endoscopic lumbar disc herniation removal
PRP is obtained from the patient's own blood, prepared, and subsequently reinjected into the patient at the end of uniportal endoscopic lumbar disc herniation removal.
Locations (1)
Hôpital Privé Jean Mermoz
Lyon, France