Clinical Research Directory

Polynucleotide-Hyaluronic Acid Gel With Xenograft for Alveolar Ridge Preservation

Sponsor: Cairo University

Summary

This randomized controlled clinical trial will evaluate the efficacy of polynucleotide-hyaluronic acid gel combined with xenograft and collagen membrane for alveolar ridge preservation following tooth extraction. Twenty participants will be randomly allocated into two parallel groups. The test group will receive xenograft mixed with polynucleotide-hyaluronic acid gel and covered with a collagen membrane, while the control group will receive xenograft with a collagen membrane alone. Clinical and CBCT assessments will be performed at baseline and during follow-up. After 6 months, ridge dimensional changes will be evaluated and core biopsies will be obtained at the time of implant placement for histological assessment.

Official title: Evaluation of the Efficacy of Polynucleotide-Hyaluronic Acid Gel With Xenograft Compared to Xenograft Alone in Alveolar Ridge Preservation: A Randomized Clinical Trial

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