Clinical Research Directory

Inclusion Criteria: 1. Male or female, aged 20-59 years 2. Obesity defined by BMI≥28 kg/m²; 3. With willingness to undergo dietary intervention for weight loss. Exclusion Criteria: 1. BMI≥40 kg/m²; 2. Suffering from gastrointestinal diseases that affect food digestion and absorption (such as functional bowel disorders, etc.), or having a known history of food allergies, or having a history of previous gastrointestinal surgery that affects dietary intervention; 3. Suffering from diseases that affect body weight or glucose and lipid metabolism (such as uncontrolled hyponatremia, thyroid dysfunction, secondary hypertension, type 1 diabetes, Cushing's syndrome, etc.); 4. Currently undergoing pharmacological treatment that affects body weight or glucose and lipid metabolism (such as thyroid medications, corticosteroids, antidiabetic drugs, lipid-lowering drugs, diuretics, etc.); 5. Having been diagnosed with clinical cardiovascular disease (coronary heart disease, stroke, heart failure, etc.) or malignancy; 6. Suffering from severe liver or kidney disease (alanine aminotransferase or serum creatinine levels exceeding 2 times the upper limit of normal); 7. Pregnant, breastfeeding, or women of childbearing potential who are not using contraception; 8. Any condition deemed by the investigator to affect study compliance; 9. Currently participating in another interventional study or having participated in another drug clinical trial within the past 3 months.